The Commerce Committee was chaired by Peter J. Daley (Majority) with Dick L. Hess (R) as Minority Chair. Williams F. Keller (D) chaired the Subcommittee on Economic Development with Adam C. Harris (R) as Vice Chair. Rosita C. Youngblood (D) chaired the Subcommittee on Financial Services and Banking with Martin T. Causer (R) as Vice Chair. Mark Longietti (D) chaired the Subcommittee on Housing with Mike Fleck (R) as Vice Chair. Jim Wansacz (D) chaired the subcommittee on Small Business with Thomas C. Creighton (R) as Vice Chair. Robert F. Matzie (D) was secretary and Mike Reese (R) was secretary of the Minority Committee.

The Commerce Committee held meetings and public hearings on the following topics: Economic Stimulation during a Recession; Economic Development and Job Creation; Check Fraud; Mortgage Foreclosure; Weatherization Assistance Program; Marcellus Shale; Neighborhood Blight; Banking; Agriculture Committee Files; and Coal Caucus Files.